Your hair products work much better and produce more even results when they reach all of your strands. It is advised that you not try to remove knots on wet hair, because that produces a high risk of hair breakage.
Spritz the detangling spray into your hair and use your fingers or a wide tooth comb to gently remove the tangles. Start working your way up inches from the bottom of your hair upwards gently. Make sure to hold the section of hair above the tangle with your free hand so you’re not pulling hair from the scalp. Before you reach for your comb, separate your hair into sections with your fingers gently. This way you can remove most of the tangles before combing your hair.